Integra LifeSciences Expands OrthoBiologics Product Line

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PLAINSBORO, N.J., Jul 13, 2009 (GlobeNewswire via COMTEX News Network) — Integra LifeSciences Holdings Corporation (Nasdaq:IART) announced today that Integra Mozaik(TM) Osteoconductive Scaffold strip is now available in a smaller configuration, broadening Integra’s OrthoBiologics portfolio and providing surgeons with a wider selection of products that will satisfy their bone grafting needs.

Integra Mozaik(TM) Osteoconductive Scaffold is designed to fill bone voids or gaps in the skeletal system of the extremities, spine and pelvis. Integra Mozaik(TM) guides the regeneration of new bone across critical defect sites in which it has been implanted. New bone formation is initiated in the matrix surface when the graft is placed in direct apposition to living host bone. The matrix is resorbed and remodeled as new bone is formed. Integra Mozaik(TM) incorporates the same Type I collagen used in several of Integra’s innovative regenerative products, including DuraGen(R) Plus Dural Regeneration Matrix, NeuraGen(R) Nerve Guide, and INTEGRA(R) Dermal Regeneration Template. Integra Mozaik(TM) combines the collagen matrix with a highly pure form of beta-tricalcium phosphate to provide both compression resistance and a mineral source, two properties essential for bone healing.

When used with bone marrow aspirate from the patient, Integra Mozaik(TM) Osteoconductive Scaffold may replace the need to harvest bone from the patient’s iliac crest, thus sparing the patient additional surgery and postoperative pain.

“The addition of this new configuration reflects Integra OrthoBiologics’ commitment to expand our orthobiologics portfolio and further Integra’s mission to provide products that improve the quality of life,” said Bill Weber, Vice President of Integra OrthoBiologics.

Degenerative disease of the spine may affect nearly all adults and is increasingly prevalent in the aging population. Patients who experience severe pain and do not respond to conservative therapies may require fusion of one or more vertebrae (spinal fusion). A spinal fusion is successful when the bones grow together biologically and form a solid mass. Bone grafts, or other materials that facilitate bone growth, are frequently used by surgeons to aid and promote bone growth to achieve this desired biological fusion.

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