Interleukin Genetics Launches Bone Health Genetic Test

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WALTHAM, MA – December 17, 2009 – Interleukin Genetics, Inc. (NYSE Amex: ILI) announced today availability of the Bone Health Genetic Test designed to detect genetic patterns associated with the development of osteoporosis-related outcomes. The test determines an individual’s risk for developing vertebral or spinal fractures and low bone mineral density. Knowing one’s genetic risk could allow an individual to take action towards building optimal bone health by following personalized guidance outlined in their genetic report, that may include recommendations for certain exercises, changing intake of Calcium and Vitamin D, as well as other lifestyle choices. The Bone Health Genetic Test is available through the Inherent Health brand of genetic tests at www.inherenthealth.com.

The Bone Health Genetic Test was developed following the completion of a 2,500-person clinical study conducted by Interleukin Genetics in collaboration with a university partner. In October at the American Society of Human Genetics 59th Annual Meeting, data from the study was presented by Interleukin Genetics that showed variations in the Interleukin 1 beta (IL1-B), Vitamin D receptor (VDR), and Estrogen receptor 1 (ESR1) genes were strongly associated with risk of spine fracture or low bone mineral density. Association between these variations and vertebral fracture or bone mineral density was determined by logistic regression analysis with adjustment for age, BMI, estrogen use and other covariates.

The Bone Health Genetic Test analyzes gene variations that were identified from the study as showing statistically significantly increased risk for spinal fracture and low bone mineral density and provides risk information beyond that provided by traditional risk factors, such as age and Body Mass Index (BMI), in the assessment of an individual’s overall risk for bone health.

“Through knowledge of one’s genetic risk for fractures and low bone density, individuals will be able to take appropriate steps to maintain strong bone health prior to any measurable signs. Through proper diet and exercise the opportunity to prevent low bone mineral density and reduce the risk of spinal fracture is significantly improved,” said Lewis H. Bender, CEO, Interleukin Genetics. “Not everyone has genetic predisposition for osteoporosis, which can progress painlessly until serious fracture occurs, but for those that do our new Bone Health Genetic Test can be a powerful preventative tool.”

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