Spine

5 key notes on the BMP-2/cancer connection in spinal fusion

By Laura Dyrda

A new study published in Spine examines the association between BMP-2 and carcinogenicity for spinal fusion patients.

The researchers reviewed 4,131 articles using the PubMed-National Library of Medicine/National Institute of Health database. The non-clinical studies directly addressing BMP-2 and cancer were included. The researchers found:

1. There were 515 articles making reference to both BMP-2 and cancer and 99 directly examined the role of BMP-2 in cancer. There were 75 in vitro studies and 24 animal studies.

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